Background and objectives: Otostegia persica (Burm.) Boiss. is an endemic plant of Iran with various applications in traditional medicine which contains of several antioxidant constituents. This research was aimed to investigate the effect of hydroalcoholic extract from O. persica aerial parts in human umbilical vein endothelial cells (HUVECs) using hydrogen peroxide (H2O2) as an inducer of oxi...

In this study, the hepatoprotective effect of the methanol extract of aerial parts (shoot) from Otostegia persica Boiss (Golder) was investigated against the carbon tetrachloride (CCl4)-induced acute hepatotoxicity in male rats. Liver damage was induced through the oral administration of 50% CCl4 in liquid paraffin (2.5 mL/Kg bw, per os) 60 min after the administration of the methanol extract o...

In an attempt to identify herbal drugs which may become useful in the prevention of diabetes, antioxidant potentials and α-amylase inhibition by the ethanol extracts of two plants belonging to Lamiaceae family, Otostegia persica and Zataria multiflora, and their different fractions were studied. Also, inhibition of α-amylase by Salvia mirzayanii and its fractions was evaluated. All of the sampl...

OBJECTIVE To evaluate the hepatoprotective properties of Otostegia persica (O. persica) ethanol extract on carbon tetrachloride-induced liver damage in rats. MATERIALS AND METHODS Fifty adult male Wistar rats were randomly divided into five groups. Group I served as normal control and was given only olive oil intraperitoneally (i.p.). Group II, III, IV, and V were administered CCl4 mixed with...

Malaria is one of the worldwide parasitic diseases which threaten the life of hundreds of millions of people at the malarious areas each year. The emergence of chloroquine-resistant strains of Plasmodium falciparum in most of the malarious areas has encountered the relevant countries with some difficulties about treating the acute cases of the disease particulary if the monotherapy regimen has ...

iran has a great wealth of various naturally occurring medicinal plants which have great potential pharmacological activities. otostegia persica (burm.f.) boiss. is one of these plants which is a perennial shrub found in south and southeast of iran. the aerial parts of o. persica have been used in iranian traditional medicine to treat various types of diseases (e.g., inflammatoryand pain-mediat...

background and objectives: otostegia persica (labiatae) is an endemic plant of iran and is used for its anti-inflammatory properties in folk medicine of sistan and baluchestan province. the aim of the present study was to investigate the anti-nociceptive and anti-inflammatory effects of o. persica different fractions and identification of the natural compounds from the most active fraction. met...

plants produce a diverse array of secondary metabolites, many of which have antimicrobial activity. otostegia persica bioss. (labiatae) grows in south east of iran. no previous investigation on antimicrobial effects of this plant has been reported. thus, the aim of this work was to examine the antimicrobial effect of o. persica extracts with different polarity on several microorganisms. aerial ...